BioProcess Online Newsletter

BioProcess Online Newsletter | February 23, 2015
	Who Is Forging Ahead In The MS Treatment Space? By Anna Rose Welch, associate editor The NIH estimates roughly $103 million of its budget will be spent on multiple sclerosis research in 2015. That seems like a small amount of money when it comes to the size of its $40 billion budget. But in doing some digging around, I’m seeing signs that there are actually quite a few players — big and small — in the academic, bio, and pharma realms working in the MS treatment space to benefit the 400,000 U.S. and 2.3 million patients globally. Sponsor Featured Content Use Of Phase Contrast Imaging To Track Morphological Cellular Changes Due To Apoptotic Activity By Brad Larson and Peter Banks, Applications Department, BioTek Instruments, Inc. Phenotypic screening, or the determination of the effects (phenotypes) that a molecule has on a cell, tissue, or whole organism, dates back to earliest drug discovery efforts. Developing A Bioreactor For Vaccines By Jose Castillo, Director of Cell Culture Technologies at ATMI LifeSciences While incremental advances can create solutions to technological problems, sometimes the only way to achieve the required result is to rip up the old rulebook and start from scratch. That’s the approach ATMI LifeSciences took in developing a bioreactor for vaccine manufacture. Effect Of Sterilization On Mechanical Properties Of Silicone Rubbers By Emilie Gautriaud, Keith T. Stafford, Jennifer Adamchuk, Mark W. Simon, and Duan Li Ou, Saint-Gobain, Northboro R&D Center Silicone rubber is widely used in the pharmaceutical industry where sterilizability is an essential requirement for all fluid transfer equipment. Pharmaceutical products must be sterilized frequently and repeatedly by high-level energy and/or chemical vapor in order to eliminate bacterial surface contamination. Maintain The Benefits Of Single-Use Technology With Cell Culture Processing By Nick Kohlstrom, Joseph Capone, and Ma Sha, Eppendorf Inc. Historically, stirred-tank bioreactors have been the standard for culturing all types of submerged cultures including suspension and anchorage-dependent mammalian, insect, yeast, plant, and microbial cultures. Featured Downloads Accurate Temperature-Sensitive Shipment Protection The Envirotainer RKN t2 container provides accurate and reliable protection for shipments of temperature-sensitive products. 3 Decisions That Impact Shipping High-Value Active Packaging Containers The worldwide distribution of high-value temperature-controlled IMPs and pharmaceutical products presents significant challenges to shippers dedicated to ensuring product quality and patient safety. Relieve Cell Culture Acidification Burdens: Hop On The Clarification Train To meet the rapidly growing demand for antibody biopharmaceuticals, which will surpass $100 billion in global sales in 2015, the process of acidification brings a number of real-life issues that must be dealt with. Expect More From Your Excipient: Syloid FP Silica Syloid FP silicas are mesoporous, amorphous, and micronized silica gels that are used as excipients in many pharmaceutical formulations due to their unique morphology. Upcoming Training Reducing Human Error In Life Sciences Manufacturing Date: Thursday, February 26, 2015 • Time: 1:00 pm to 2:30 pm EST Featured Products And Services Cell Counter For Cell Viability Analysis The Vi-CEL Cell Counter provides an automatic means to perform the trypan blue dye exclusion method, allowing users to load up to 10 samples at once for easy and automated cell viability analysis. Download Brochure • Request Information Beckman Coulter Life Sciences Enhanced Process Flexibility With Back-To-Back Insert Adapters MPC/MPX back-to-back insert adapters from CPC solve end user issues when presented with the challenge of making a connection with identical female connector halves. Download Brochure • Request Information CPC BioPAT Chemometrics Toolbox Integrating and merging the capabilities of advanced chemometric methods into our scalable process control software, BioPAT MFCS/win enables both operators and management to look into systematic cost savings while ensuring process reliability, safety, and robustness. Download Brochure • Request Information Sartorius Stedim Biotech PRIME-XV Neural Progenitor Cell Expansion Xeno-Free, Serum-Free Medium PRIME-XV supports the expansion of human, rat, and mouse neural progenitor cells. It maintains neural progenitor cell potential to differentiate into neurons, oligodendrocytes, and astrocytes. Download Datasheet • Request Information Irvine Scientific Subscribe Today   For insight on how pharma and biopharm executives can improve how they run their businesses, subscribe to Life Science Leader magazine.