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Posted: 08 Feb 2015 12:27 PM PST
Combining experimental data from X-ray crystallography, NMR spectroscopy, cryoelectron microscopy and lipidomics, researchers have built a complete model of the outer envelope of an influenza A virion for the first time. The approach, known as a coarse-grained molecular dynamics simulation, has allowed them to generate trajectories at different temperatures and lipid compositions -- revealing various characteristics that may help scientists better understand how the virus survives in the wild or find new ways to combat it.
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Posted: 08 Feb 2015 12:27 PM PST
By employing derivatives of humanin, a naturally occurring peptide encoded in the genome of cellular mitochondria, researchers are working to interrupt necrosis, buying precious time for tissues whose cellular mechanisms have called it quits.
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Posted: 08 Feb 2015 12:27 PM PST
A large percentage of the world's population -- fully one third, by the World Health Organization's estimates -- is currently overweight or obese. This staggering statistics has made finding ways to address obesity a top priority for many scientists around the globe, and now a group of researchers has found promise in the potential of capsaicin -- the chief ingredient in chili peppers -- as a diet-based supplement.
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Posted: 08 Feb 2015 12:27 PM PST
Not unlike an urban restaurant, the success of a bacterial cell depends on three things: localization, localization and localization. But the complete set of controls by which bacteria control the movement of proteins and other essential biological materials globally within the confines of their membrane walls has been something of a mystery. Now, researchers have parsed out the localization mechanisms that E. coli use to sort through and organize their subcellular components.
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