2015년 2월 20일 금요일

Structure-based design used as tool for engineering deimmunized biotherapeutics

02/20/2015 01:04 PM EST

the P99 beta lactamase peptide backbone
In the first experimental use of algorithms that employ structure-based molecular modeling to optimize deimmunized drug candidates, Dartmouth researchers complement their prior sequence-based deimmunizing algorithms and expand the tool kit of protein engineering technologies to use in next generation drug development.

Full story at http://cancer.dartmouth.edu/about_us/newsdetail/72919/

Source
The Geisel School of Medicine at Dartmouth

This is an NSF News From the Field item.

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