Merck Champions Single-Use By Addressing Emotion vs. Science

Merck Champions Single-Use By Addressing Emotion vs. Science By Trisha Gladd, Editor, Pharmaceutical Online and BioProcess Online Lowering the cost of medication is the key to the U.S. gaining a stronghold on the global pharmaceutical market. As anyone knows, in order to lower the cost of medication, the cost of manufacturing will need to be lowered as well. According to Chris Smalley, Ph.D., director of validation compliance at Merck, single-use technology (SUT) could be the hero. Featured Content Automation Of A Homogeneous Proximity Assay For Immunogenicity Testing Of Biological Drug Products By P. Brescia and P. Banks BioTek Instruments, Inc. Several challenges have surfaced during clinical evaluation of biological drug products due to a commonly associated immune response in patients. Antidrug antibodies (ADA) are known to be frequently generated during administration of humanized monoclonal antibody therapeutics. Air Particle Counters Resistant To Vapor Hydrogen Peroxide (VHP) By Ted Lawrence The use of vaporous hydrogen peroxide (VHP) is commonplace in the pharmaceutical industry for disinfecting sterile manufacturing cores. Since VHP is a strong oxidizing agent it can be damaging to certain internal components in optically based air particle counting instruments. Improve Purification Of Carbohydrate-Based Drugs By Rakesh Bose, Scott Anderson, Kathy Lawrence, and Melissa Wilcox, Grace Carbohydrates are commonly found as constituents in plants, animals, and microorganisms. Carbohydrate units have considerable applications in medicine when bound to lipids, peptides, proteins, or even nucleic acids. Due to their therapeutic effects, conjugation of carbohydrates and their presence in antibiotics can be effectively used to find cures for the treatment of various diseases. Removal Of Endotoxin From Monoclonal Antibodies By Brendan Fish, Karen Bannister, and Emma Tribbeck, Cambridge Antibody Technology It is desirable to minimize endotoxins in purified protein preparations prior to their use in cell-based assays. Vivapure centrifugal anion exchange membrane devices can remove endotoxin from research-grade monoclonal antibody solutions simply with high protein recovery. Featured Downloads Development Of Low Pyrogenic Response And Ultra-Low Metal Ion Extractables Zeta Plus Filter Medium Cellulose based depth filters are widely used for filtration of biopharmaceutical and blood plasma fraction therapeutics. This application brief describes development of two cellulose based depth filters (the LA and LP grades), employing a specialized grade of cellulose selected to minimize beta glucan extractables. 0.2 Sterilizing Capsule Filter ASI offers MDI 0.2 sterilized filters on standard bag sizes from 1-liter to 200-liter 2D bags. ASI can produce any size and any type of bag upon request. ASI can also supply any filter and any size upon request. CELLROLL And CELLSPIN Cell Cultivation Systems The CELLROLL and CELLSPIN systems are based on a modular assembly concept that allows you to configure and combine the two instruments according to your needs. Pure Sericin: Silk Protein Pure Sericin is applicable as a useful component of serum-free media. A protein derived from silkworms is used for stimulation of cell proliferation, suppression of cell death, and cryopreservation of cells. Featured Products And Services Parenteral Solutions Whether your project is a liquid small-volume parenteral or a liquid large-volume parenteral, rely on Patheon for expertise in the development, optimization, and scale-up of these complex formulations. Download Datasheet • Request Information Patheon Inc. Recombinant Human IL-3 ACF Animal Component Free IL-3 is a pleiotropic cytokine produced primarily by activated T-cells, but it is also produced by mast cells and monocytes. • Request Information Irvine Scientific CrimpLoc Closure System ILC Dover pioneered flexible containment for the pharmaceutical industry and continues to innovate processes for better performance. Download Brochure ILC Dover Single-Use And Ready-To-Use Biopharmaceutical Products GE Healthcare Life Sciences's single-use and ready-to-use technologies, ReadyToProcess and Xcellerex, play a crucial role in providing the flexibility to support multiproduct facilities. GE Healthcare Life Sciences Subscribe Today   For insight on how pharma and biopharm executives can improve how they run their businesses, subscribe to Life Science Leader magazine.