7 CEOs Say It's About The "Bios": Biotechs, Biopharmaceuticals, And Biosimilars

BioProcess Online Newsletter | March 16, 2015
	7 CEOs Say It's About The "Bios": Biotechs, Biopharmaceuticals, And Biosimilars By Louis Garguilo, Executive Editor, Outsourced Pharma The booming “Bios” are spurring expenditures, supply-and-demand questions and business decisions, and grabbing the attention of CEOs in 2015. Featured Content Assess Drug Residence Time And Antimetastatic Effects Of CXCR4 Inhibitors By Brad Larson, Leonie Rieger, Nicolas Pierre, and Hilary Sherman, BioTek Instruments Metastasis, the spread of cancer cells from the original tumor to secondary locations within the body, is linked to approximately 90 percent of cancer deaths. Biosimilar Interferon a-2a: Development Of A Cost-Effective, Robust, And Flexible Process This application note describes the rapid development of a production process for a biosimilar molecule, interferon α-2a, expressed in E. coli. Screening of modern chromatography media for downstream purification was done either with small packed columns and an ÄKTA avant system or with PreDictor plates (96-well prefilled filter plates). Filtration Of Cell Culture Growth Media And Process Buffers Media feeds and process buffers are two universal additives to biopharmaceutical processes. Media feeds are added to a fermenter to facilitate growth of mammalian, yeast, insect, and bacterial cells. How Ready-To-Use PAT Solutions Allow Pharma To Achieve Efficiency And Reduce Costs By Dan Kopec, Sartorius Stedim Biotech Process analytic technology (PAT) can be summarized as a driver for change from "status quo" offline laboratory analytics for data collection and subsequent post-process analysis to "dynamic," online monitoring and real-time decision making with automated control. Featured Downloads Why A Closed-Loop Supply Chain System? This article covers improving compliance and efficiency in the pharmaceutical supply chain with reduced cost and risk. How does the sponsor ensure that product transfer conforms to the same established written procedures demanded at the investigator level throughout the full length of the supply chain, or more specifically, while in the hands of nonpharmaceutical, noninvestigator personnel? Accurate Temperature-Sensitive Shipment Protection: Envirotainer RKN t2 The Envirotainer RKN t2 container provides accurate and reliable protection for shipments of temperature-sensitive products. Stringent SOPs And 24/7 Service Smooth Transport And Secure Trust World Courier's clients often have stringent security requirements and complex logistics needs. That's why many clients select World Courier — because in some cases, there are quite literally no other providers who can meet the clients' high standards for service. In this case, World Courier partnered with a customer focused on the research, development, and manufacturing of products to treat life-threatening diseases. Three60 Sampling System Brochure The simple design behind the Three60 Sampling System allows you to take a representative sample of your product with minimal effort. Featured Products And Services Spent Media Analysis To complement our media development and optimization services, Irvine Scientific offers Spent Media Analysis. This analysis provides an understanding of changes in culture conditions over time. Irvine Scientific can provide data within approximately 10 business days. • Request Information Irvine Scientific Syloid FP Silica Excipients Syloid FP silicas are the intelligent choice for many pharmaceutical applications due their unique morphology. The combined adsorption capacity, porosity, particle size, and greater internal surface area allow it to provide several benefits simultaneously that can help minimize the number of excipients required, expedite manufacturing, and improve efficacy of the final dosage form. Download Brochure • Request Information Grace E-4031 For Cell Membrane Study E-4031 is a specific blocker of delayed rectifier current (Ikr). Its selectivity for the small and rapidly activating component of Ikr makes it a useful tool for analyzing K+ channel activity in heart cells. • Request Information Wako Laboratory Chemicals Safe Handling Of Cytotoxic Compounds A limited number of companies have the capabilities of handling cytotoxic compounds safely and efficiently, and even fewer offer expertise in R&D. BTL is unique in now being able to bring together its R&D expertise in the lyophilization of products with a dedicated facility for cytotoxic products. Download Brochure • Request Information Biopharma Technology Limited Subscribe Today   For insight on how pharma and biopharm executives can improve how they run their businesses, subscribe to Life Science Leader magazine.